Table 2.
Hemodynamic and morphometry data obtained from either sham or 3-wk I/R groups
| Sham | Sham + Epicatechin | I/R | I/R + Epicatechin | ||||
|---|---|---|---|---|---|---|---|
| Hemodynamics | |||||||
| Group size | 5 | 4 | 7 | 8 | |||
| HR, beats/min | 318±12 | 328±11 | 290±6 | 302±18 | |||
| LVPSP, mmHg | 119±2.2 | 116±6.2 | 108±2 | 108±4 | |||
| LVEDP, mmHg | 6.9±1.1 | 2.6±0.2 | 6.1±0.8 | 5.5±1.5 | |||
| MAP, mmHg | 94±4.7 | 92±11 | 89±2 | 85±4 | |||
| Morphometry | |||||||
| Group size | 5 | 4 | 7 | 8 | |||
| HW/BW | 3.2±0.2 | 3.2±0.5 | 4.5±0.2* | 4.5±0.2* | |||
| Outer LV diameter, mm | 1.6±0.1 | 1.6±0.1 | 1.6±0.06 | 1.6±0.04 | |||
| Inner LV diameter, mm | 0.53±0.02 | 0.52±0.08 | 0.52±0.06 | 0.55±0.05 | |||
| AW thickness, mm | 0.52±0.05 | 0.53±0.05 | 0.4±0.03† | 0.41±0.02 | |||
| SW thickness, mm | 0.49±0.05 | 0.47±0.04 | 0.62±0.04 | 0.49±0.03 | |||
Values shown are mean ± SE. MAP, mean arterial pressure; HW/BW, heart weight-to-body weight ratio; LV, left ventricle; AW, anterior wall; SW, septal wall. Epicatechin groups were pretreated for 10 days.
*
P < 0.01 vs. sham
†
P < 0.01 vs. I/R SW thickness.