Table 2.
Constructs |
Rc (min−1)a |
---|---|
DMPC | 8.1 × 10−4 |
B5.9 | 9.5 × 10−4 |
B6.4−10 | 2.6 × 10−3 |
B6.4−13 | 2.9 × 10−3 |
B6.4−15 | 2.7 × 10−2 |
B6.4−17 | 5.5 × 10−3 |
B9−13 | 1.1 × 10−3 |
B13−15b | 1.24 |
Rc is the reciprocal of T1, which is obtained by fitting the curve in Fig. 4 with a first exponential decay y = Ae-x/T1 + B using Origin 7.5.
Only the first 2 minutes in the clearance assay are used in the curve fitting for B13−15.