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. Author manuscript; available in PMC: 2008 Aug 25.
Published in final edited form as: Anal Chem. 2007 Feb 13;79(6):2312–2319. doi: 10.1021/ac061986j

Table 1.

Comparison of QCM biosensors for the detection of E. coli

References E. coli strains Assay principle LOD (cells/mL) Linear ranges (cells/mL)
8 K-12 Immunosensor: Anti-ECA antibody cross-linked to PEI precoated surface 106 106-109
17 O157:H7 Immunosensor: Antibody linked to MHDA SAM 103 103-108
51 O157:H7 DNA sensor: Nanoparticle amplification 2.67 × 102 2.67 × 102-2.67 × 106
Our results E. coli strains Assay principle Reliable quantitative detection (cells/mL) Linear ranges (cells/mL)
W1485 Carbohydrate sensor 3.0 × 107 2.9 × 107-2.7 × 108
W1485 Carbohydrate/lectin sensor 7.5 × 102 7.5 × 102-7.5 × 107

ECA: Enterobacterial common antigen; PEI: polyetheneimine; MHDA: 16-Mercaptohexadecanoic acid; SAM: self-assembled monolayer