TABLE 3.
Agreement between the new ELISA and the reference ELISAs with sera from hepatitis E patients or other patient control groups
| New ELISA result | No. of samples with the following reference ELISA resulta:
|
% Agreement | Kappa statisticb | |
|---|---|---|---|---|
| Positive for IgM or IgG antibodies | Negative for IgM and IgG antibodies | |||
| Positive | 265 | 2 | 97.8 | 0.944 |
| Negative | 6 | 93 | 97.9 | |
a
Data generated by the two reference ELISAs were combined and compared with those generated by the new ELISA for the calculation of agreement. The negative results used for the calculation of agreement were from the disease controls only.
b
Calculated for the total agreement of 97.8%. A kappa statistic of ≥0.75 represents excellent agreement, one of 0.40 to 0.75 represents good to fair agreement, and one of <0.40 represents poor agreement (20).