FIG. 3.

Quantification of granulomatous infiltration in aerosol-infected mice's lung. After infection, mice were treated with INH/RPN from weeks 6 to 14 (in white) and with two subcutaneous inoculations of RUTI at weeks 14 and 17 (in black) or BCG at week 14 (in gray). Also shown are the percentages of pulmonary infiltration, which were obtained by dividing the area of granulomatous infiltration by the total area of the lobes, multiplied by 100. Values represent the means and SD. An asterisk indicates significant differences (P < 0.05 by t test). The color of the asterisk corresponds to the group with lower values to which the comparison was significant. Black and gray asterisks refer to RUTI and BCG groups, respectively.