FIG. 1.

Determination of levels of IL-1β secreted from macrophages infected with different Y. pestis or Y. pseudotuberculosis strains. BMDMs were left uninfected or infected with the indicated strains of Y. pestis or Y. pseudotuberculosis (Table 1). IL-1β levels in the supernatants of BMDMs at 24 h postinfection were measured by ELISA. Results shown are the averages from three independent experiments. Error bars represent standard deviations. Statistical significance compared to KIM5 (B) or IP2666 (C and D) was determined (P < 0.01, **; P < 0.001, ***).