TABLE 1.
Antigens of the mycobacterial abundant invariomea
| Rv no. | Designation | Avg mRNA concn (ppm) | SD (ppm) | Reference |
|---|---|---|---|---|
| Rv0288 | CFP-7 | 781 | 286 | 23 |
| Rv0440 | GROEL-2 | 4,438 | 2,385 | 21 |
| Rv1174c | MPT8.4 | 1,165 | 424 | 6 |
| Rv1886c | FBPB/AG85B | 1,464 | 1,168 | 12 |
| Rv1987 | Rv1987 | 495 | 136 | 4 |
| Rv1980c | MPT64 | 1,316 | 629 | 11 |
| Rv3418c | GROES | 5,189 | 2,593 | 2 |
| Rv3616c | Rv3616c | 2,619 | 1,457 | 15 |
| Rv3874 | CFP-10 | 5,414 | 3,950 | 24 |
| Rv3875 | ESAT-6 | 2,472 | 1,229 | 3 |
a
mRNA levels are expressed in parts per million and are averages of the expression levels for six growth conditions for both M. tuberculosis and M. bovis. For comparison, for M. tuberculosis growing aerobically in chemostats the expression levels ranged from 17 to 13,634 ppm, with a median of 133 ppm; the 85th percentile boundary in this data set was 359 ppm.