FIG. 2.

Anti-P. gingivalis IgG production is impaired in female BALB/c-IL-17RA^KO mice. (A) WT and IL-17RA^KO mice exhibit anti-P. gingivalis antibody responses. Serum anti-P. gingivalis IgG was evaluated in P. gingivalis-infected mice by ELISA, and means ± standard deviations are shown. *, P < 0.05. Pg, P. gingivalis. (B) Net antibody titer is impaired in female mice. The titer is defined as the antibody titer of sham-treated mice subtracted from that of P. gingivalis-infected mice. Standard deviations are shown, and statistical significance was assessed by an unpaired t test. *, P < 0.05; n.s., not statistically different.