TABLE 1.
Species | No. of isolates tested | Results for:b
|
|||||
---|---|---|---|---|---|---|---|
ANID
|
CASP
|
MICA
|
|||||
MIC90 | % ≤ 2 | MIC90 | % ≤ 2 | MIC90 | % ≤ 2 | ||
C. albicans | 2,869 | 0.06 | 100 | 0.06 | 100 | 0.03 | 100 |
C. glabrata | 747 | 0.12 | 99.9 | 0.06 | 99.9 | 0.015 | 100 |
C. tropicalis | 625 | 0.06 | 100 | 0.06 | 99.8 | 0.06 | 100 |
C. krusei | 136 | 0.06 | 100 | 0.25 | 100 | 0.12 | 100 |
C. parapsilosis | 759 | 2 | 92.5 | 1 | 99.9 | 2 | 100 |
C. guilliermondii | 61 | 2 | 90.2 | 1 | 95.1 | 1 | 100 |
All Candida spp. | 5,346 | 2 | 98.8 | 0.25 | 99.9 | 1 | 100 |
MICs were determined in RPMI broth with 24-h incubation and prominent-inhibition endpoint. Data were compiled from reference 55.
% ≤ 2, percentage of isolates for which the MIC was 2 μg/ml or less. Abbreviations: ANID, anidulafungin; CASP, caspofungin; MICA, micafungin.