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. 2008 Jun 25;46(8):2620–2629. doi: 10.1128/JCM.00566-08

TABLE 6.

Relationship between MIC and outcome for treatment of invasive candidiasis with andidulafungin and micafungina

MIC (μg/ml)b Results for:c
Anidulafungin
Micafungin
S/T % S/T %
0.008 67/70 96
0.016 11/14 79 120/149 81
0.03 11/13 85 116/152 76
0.06 8/9 89 12/13 92
0.125 1/3 33 12/14 86
0.25 1/1 100 15/17 88
0.5 4/5 80 19/25 76
1 3/5 60 28/31 90.3
2 2/2 100 5/9 56 (71)d
Total 119/135 88 327/410 80
Total ≤2 119/135 88 327/410 80
a

Data were compiled from references 30, 45, and 56.

b

MICs were determined in accordance with the standards of CLSI document M27-A3 (11). Total ≤2, total number of patients for whose isolates the drug MIC was 2 μg/ml or less.

c

S/T, number of patients successfully treated/total number treated.

d

Five of 7 patients infected with C. parapsilosis for which the MIC was 2 μg/ml were treated successfully.