TABLE 3.
Rv2629 A191C allele and drug resistance in Asian and non-Asian isolates
| Susceptibility profilea | Rv2629 191 allele
|
P | |
|---|---|---|---|
| C [no. (%)] | A [no. (%)] | ||
| Asian | |||
| RIF resistant | 24 (64.9) | 13 (35.1) | 0.003 |
| RIF susceptible | 16 (32.7) | 33 (67.3) | |
| INH resistant | 31 (55.4) | 25 (44.6) | 0.025 |
| INH susceptible | 9 (30.0) | 21 (70.0) | |
| EMB resistant | 18 (51.4) | 17 (48.6) | 0.449 |
| EMB susceptible | 22 (43.1) | 29 (56.9) | |
| STR resistant | 19 (45.2) | 23 (54.7) | 0.817 |
| STR susceptible | 21 (47.7) | 23 (52.3) | |
| Non-Asian | |||
| RIF resistant | 6 (9.8) | 55 (90.2) | 0.875 |
| RIF susceptible | 9 (9.1) | 90 (90.9) | |
| INH resistant | 6 (8.8) | 62 (91.2) | 0.837 |
| INH susceptible | 9 (9.8) | 83 (90.2) | |
| EMB resistant | 3 (6.5) | 43 (93.5) | 0.432 |
| EMB susceptible | 12 (10.5) | 102 (89.5) | |
| STR resistant | 7 (13.0) | 47 (87.0) | 0.266 |
| STR susceptible | 8 (7.6) | 98 (92.5) | |
a
RIF, rifampin; INH, isoniazid; EMB, ethambutol; STR, streptomycin.