TABLE 2.
Seven lytic transglycosylases are encoded in the gonococcal genome
| Gonococcal lytic transglycosylase | Function | E. coli homologue | % Identity/range (amino acids) | Meningococcal homologue |
|---|---|---|---|---|
| LtgA (NGO2135) | PG monomer production | Slt70 | 25/556 | +a |
| LtgB (NGO1033) | Unknown | MltC | 33/199 | + |
| LtgC (NGO2048) | Cell separation | MltA | 21/441 | GNA33 |
| LtgD (NGO0626) | PG monomer production | MltB | 48/123 | MltB |
| LtgE (NGO0608) | Unknown | MltD | 34/341 | + |
| LtgXb (NGO5004) | Type IV secretion | F-plasmid ORF169 | 33/129 | +/−c |
| AtlAb (NGO5025) | Type IV secretion | Lambda endolysin | 38/158 | −d |
a
Homologue present.
b
GGI-encoded lytic transglycosylase.
c
Homologue present in some strains.
d
Homologue not detected.