TABLE 2.

Amino acid changes of HCV variants recovered from chimpanzee 1494 after transfection with pCV-H77C^a

Sample	Amino acid encoded by HCV genome region at indicated polyprotein position
	E2		p7		NS2	NS3	NS4B	NS5A		NS5B
	463	735	763	789	859	1202	1964	2279	2365	2483
H77C	T	L	H	A	V	G	I	R	T	H
HCV recovered at wk:
2						•
4						G/e
9	•	•	•	•	•	E/g	•	•	•	•
21	I	L/V	Y	T	M	E	L	Q	A	Y

^aThe sequence of H77C is shown on the top. Amino acids identical with H77C are indicated with dots. Dominant changes are indicated by capital letters. Minor sequences are indicated with lowercase letters. Only a short sequence encoding amino acid 1202 was analyzed for weeks 2 and 4.