TABLE 2.
Virus | Logit regressiona
|
Time to deathb
|
||||||
---|---|---|---|---|---|---|---|---|
LC50 (OBs/ml)
|
Relative potency | P | Mean (h) | 95% Confidence limit
|
||||
Mean | 95% Confidence limit
|
|||||||
Low | High | Low | High | |||||
SfWT | 2.9 × 104 | 1.7 × 104 | 4.8 × 104 | 1.0 | 110 a | 105 | 116 | |
SfBc | 9.3 × 104 | 5.5 × 104 | 1.1 × 105 | 0.31 | <0.001 | 120 a | 114 | 125 |
Sfbac | 1.0 × 105 | 6.1 × 104 | 1.7 × 105 | 0.28 | <0.001 | 123 a | 116 | 130 |
Sf29null | 1.5 × 106 | 8.2 × 105 | 2.9 × 106 | 0.02 | <0.001 | 157 b | 147 | 167 |
Sf29null-repair | 2.1 × 105 | 1.2 × 105 | 3.5 × 105 | 0.13 | <0.001 | 132 a | 125 | 140 |
Logit regressions were fitted using the GLIM program with a common slope of 0.7847 ± 0.0695 (mean ± standard error). A test for nonparallelism was not significant (χ2 = 6.374, df = 4, P = 0.173). Relative potencies were calculated as the ratio of effective concentrations relative to the SfWT isolate. P values were calculated by a t test of the differences between regression intercepts compared to that of the SfWT isolate.
MTDs were estimated by Weibull analysis (8). MTDs labeled with different letters were significantly different.
SfB data are from reference 48.