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. 2008 Jun 11;82(16):7768–7772. doi: 10.1128/JVI.00653-08

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Copyright © 2008, American Society for Microbiology

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FIG. 2. — Schematic of the model. Virus grows initially at rate r and is later reduced through killing of infected cells by activated CTL. Epitope-specific pMHC on activated DC, P_i, are created in proportion to the virus load at rates f₁ and f₂ for the NP366 and PA224 epitopes, respectively. Unactivated CTL, T_i, are activated by their cognate epitope at rates a_i. Activated CD8 T cells, , proliferate at rates g_i and reduce virus at rates k_i. Equations and more details are given in the text.

Inline graphic — Schematic of the model. Virus grows initially at rate r and is later reduced through killing of infected cells by activated CTL. Epitope-specific pMHC on activated DC, P_i, are created in proportion to the virus load at rates f₁ and f₂ for the NP366 and PA224 epitopes, respectively. Unactivated CTL, T_i, are activated by their cognate epitope at rates a_i. Activated CD8 T cells, , proliferate at rates g_i and reduce virus at rates k_i. Equations and more details are given in the text.