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. 2008 Jun 18;82(17):8592–8604. doi: 10.1128/JVI.00499-08

FIG. 2.

FIG. 2.

Cleavages of the DuckHepBFlipPPT mutants by the RNase H of RSV RT. The arrows depict the positions of the PPT miscleavages, which result in insertions of part or all of the PPT (simple PPT inserts) or small deletions of the U3. The positions of the cleavages are inferred from the analysis of the 2-LTR circle junctions. The arrows at the top represent the results from one experiment, and the arrows at the bottom represent the results from a second, independent experiment. The sizes of the arrows are related to the number of events (denoted by a number above and/or below the arrows). The line delineates the original border between the PPT and the U3 and, in the case of the DuckHepBFlipPPT4 mutant, where there were cleavages at this junction. The numbers above and below the line are the numbers of consensus sequences found in two experiments. The underlined nucleotides were mutated.