Schematic representation of mature extracellular virions. The viral composition of the capsid, tegument, and envelope is indicated. The diameter of each circle indicates the relative abundance of the proteins based on their NQPCT score (see Materials and Methods). Given the semiquantitative nature of this score, they are grouped into low abundance (<1% of total proteins), medium abundance (1 to 4%), high abundance (5 to 10%), and very high abundance (>10%). The potential cellular components identified in Table 3 have been omitted since they are in need of validation. However, all but one of them (profilin-1) falls within the first two lowest abundance brackets.