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Internalization of α-factor is normal in S(all)A Clc1p cells. Uptake of radiolabeled α-factor was measured as described in MATERIALS AND METHODS in congenic clc1Δ cells containing an integrated copy of wild-type (WT) CLC1 (GPY1970) or S(all)A clc1 (GPY1973). Each experiment was performed in duplicate, and the values at each time point were averaged. Data are the mean ± SD for three experiments.
