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Protein structure of stabilin-2 and alignments of the EGF-like domains. (A) Domain structure of stabilin-2. Stabiln-2 contains four EGF-like domain repeats (EGRrps, E1 to E4). Each EGFrp consists of two atypical EGF-like domains and four standard EGF-like domains (the fourth EGFrp [E4] has three EGF-like domains). (B) Alignment of the EGF-like domains in stabilin-2. The consensus sequences of atypical and standard EGF-like domains are derived from previous studies (6, 22, 39).
