Fig. 1.
Wild-type mice (Wt) and Gipr−/− mice were ovariectomized (OVX) or sham operated (Sham; n = 10 in each group). A: body weight alterations over 26 wk. AUC of body weight during the observation period was significantly increased in wild-type mice. B: NMR analysis of change in body fat; representative results from monthly measurements in weeks 14 and 26 after surgery. Body fat was increased only in wild-type mice after ovariectomy (*P < 0.05; **P < 0.01).