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. 2008 May 20;295(2):E305–E312. doi: 10.1152/ajpendo.00512.2007

Fig. 3.

Fig. 3.

Relative gene expression of transforming growth factor-β1 (TGF-β1; A) and Smad7 (B) by QRT-PCR analysis and phospho-Smad2 (p-Smad2) by Western blot analysis (expressed as means ± SE) (C). A: Sham and ADX+Aldo groups showed higher expression of TGF-β1 mRNA than ADX and ADX+ANG II groups. B: Sham and ADX+Aldo groups showed lower expression of Smad7 mRNA than ADX and ADX+ANG II groups. C: there was a higher p-Smad2 level in Sham and ADX+Aldo groups than in ADX and ADX+ANG II groups and a slightly increased level in the ADX+ANG II group compared with the ADX group. Densitometric quantification is also shown (1 representative blot of 3) *P < 0.001 vs. ADX+ANG II; †P < 0.01 vs. ADX; ‡P < 0.05 vs. ADX; §P < 0.001 vs. ADX; ‖P < 0.05 vs. ADX+ANG II.