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Effect of H3 (100 and 1,000 nM) on the release of gonadotropins from in vitro anterior pituitary fragments [data shown as %basal release with basal artificial cerebrospinal fluid (aCSF) indicated as 100%]. A: LH; B: FSH. GnRH was used as a positive control. ***P < 0.001 vs. basal aCSF by ANOVA with post hoc Tukey's test, n = 24/group.
