Fig. 5.

PI3K/Akt pathway in PDGF-induced tube formation. The role of PI3K in tube formation induced by PDGF was examined using PI3K inhibitors. A: representative images of tube formation of the endothelial cells induced by PDGF. B: quantification of tube formation. C: representative Western blots of phosphorylation of PI3K/Akt signaling molecules. D: quantification of Western blot signals. In this figure, all experiments were repeated 3 times with consistent results. Each data point represents mean ± SE (n = 3 experiments).