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. Author manuscript; available in PMC: 2008 Aug 25.

Published in final edited form as: Chem Res Toxicol. 2006 May;19(5):614–621. doi: 10.1021/tx060025x

(a) Formation of 5-FodU, 5-HmdU, and 8-oxodG under different oxidation conditions. (b) Formation of d(G^T) under different oxidation conditions. The data represent mean ± SD from three independent experiments. No Cu2+: 400 μM H₂O₂ and 4 mM ascorbate; No ascorbate: 400 μM H₂O₂ and 50 μM Cu²⁺; with DMSO: 400 μM H₂O₂, 50 μM Cu²⁺, 4 mM ascorbate and 8 mM DMSO; without DMSO: 400 μM H₂O₂, 50 μM Cu²⁺ and 4 mM ascorbate.

(a) Formation of 5-FodU, 5-HmdU, and 8-oxodG under different oxidation conditions. (b) Formation of d(G^T) under different oxidation conditions. The data represent mean ± SD from three independent experiments. No Cu2+: 400 μM H₂O₂ and 4 mM ascorbate; No ascorbate: 400 μM H₂O₂ and 50 μM Cu²⁺; with DMSO: 400 μM H₂O₂, 50 μM Cu²⁺, 4 mM ascorbate and 8 mM DMSO; without DMSO: 400 μM H₂O₂, 50 μM Cu²⁺ and 4 mM ascorbate.