Fig. 3.
Acute serosal losartan (10−4 M) does not alter sodium fluxes across distal colonic tissues removed from CON rats (n = 9), but Isc is significantly decreased. Error bars represent ±1 SE above or below the mean of data in each group. An asterisk indicates a significant difference between Per I (CON) and Per II (+LOS), using a paired t-test, P ≤ 0.05. Transepithelial conductance (GT) was not significantly changed in Per II (9.94 ± 1.05 mS/cm2) compared with Per I (10.37 ± 1.08 mS/cm2).