Fig. 1.
A: colonic compliance curves for normal, overweight, and obese subjects. The P50, the pressure at which half of the maximum volume is reached, was significantly higher in overweight or obese participants, indicating decreased compliance or higher stiffness of the colonic wall (P = 0.0006, adjusted by age and sex). B: colonic compliance data plotted for women and men showing similar patterns with higher P1/2 in obesity and no significant differences between women and men. BMI, body mass index.