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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Brain Behav Immun. 2007 Dec 18;22(5):717–726. doi: 10.1016/j.bbi.2007.10.010

Figure 1. Sociability and lymph node innervation.

Figure 1

Catecholaminergic neural fibers were mapped using glyoxylic acid chemofluorescence to define structural varicosities containing the sympathetic neurotransmitter norepinephrine within the lymph node parenchyma (a) or surrounding blood vessels (b). (c) Parenchymal and perivascular innervation density was compared across lymph nodes biopsied from adult male rhesus macaques characterized as High Sociable and Low Sociable. (d) Relationship between mean parenchymal innervation density for each animal and Sociability levels expressed as a continuous dimension of individual differences (z-score). The solid regression line summarizes the linear relationship between innervation density and Sociability for all animals analyzed (Spearman r = −.642, p =.119) and the dashed regression line shows the same relationship after exclusion of the high-range outlier (r = −.846, p =.034).