TABLE 1.

Characteristics of PPARGC1A SNPs genotyped in 959 subjects

SNP name*	rs no.	HUGO name†	Distance from TSS (bp)‡	Gene region	Minor allele frequency
m9722	rs10030083	NT_006316.15g0.14767780C>A	−9,722	Upstream	0.19 ± 0.01
m1668	rs2970869	NT_006316.15g0.14568727G>A	−1,668	Upstream	0.26 ± 0.01
i5378	rs2946385	NM_013261.3r0.234 + 52G>T	5,378	Intron 2	0.43 ± 0.02
i15867	Rs10028665	NM_013261.3r0.234 + 10541C>T	15,867	Intron 2	0.16 ± 0.01
i27289	rs4235308	NM_013261.3r0.2:34 + 21963A>G	27,289	Intron 2	0.39 ± 0.02
i55301	rs4697046	NM_013261.3r0.235–3026A>G	55,301	Intron 2	0.37 ± 0.02
G482S	rs8192678	NP_037393.1p.Gly482Ser	76,089	Exon 8	0.29 ± 0.01
T612M	rs3736265	NP_037393.1p.Thr612Met	76,994	Exon 9	0.06 ± 0.01
3U4898	rs3774923	NM_013261.3r0.4778G>A	96,637	3′-Untranslated region, exon 13	0.04 ± 0.01

Data are means ± SE.

^*m indicates a SNP is located in the promoter or upstream of the gene; i is in the intron; 3U is in the 3′-untranslated region; and others are substitution changes in exons.

^†HUGO names of SNPs are based on nomenclature recommendations of the Human Genome Variation Society (http:/www.hgvs.org/rec.html).

^‡TSS, transcription start site.