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. 2008 Jun 4;295(2):R535–R542. doi: 10.1152/ajpregu.00043.2008

Fig. 3.

Fig. 3.

A: effect of intracerebroventricular scrambled oligodeoxynucleotide (ODN) pretreatment on cardiovascular and renal excretory responses to central N/OFQ in conscious Sprague-Dawley rats. The values are expressed as means ± SE and illustrate the cardiovascular and renal effects of intracerebroventricular N/OFQ (5.5 nmol) in six conscious rats that were pretreated (24 h) with intracerebroventricular scrambled ODN (25 μg). Data for intracerebroventricular N/OFQ are transposed from Fig. 1 for comparison. Abbreviations are the same as in Fig. 1. *P < 0.05 compared with respective group control value (designated C). B: representative immunoblot showing GAPDH, Gαq and Gαz subunit protein levels in brain cortex (BC), hypothalamus (H), and medulla (M) sample from a male Sprague-Dawley rat that was pretreated (24 h) with intracerebroventricular scrambled ODN (25 μg) or saline vehicle (5 μl).