Figure 1.

Effect of MβCD on transferrin (●) and ricin (○) endocytosis. MDCK II cells were washed briefly in HEPES-buffered medium before incubation with and without the indicated concentrations of MβCD for 15 min at 37°C. ¹²⁵I-labeled transferrin or ¹²⁵I-labeled ricin was then added to the cells, and the amounts of endocytosed transferrin or ricin were measured as described in MATERIALS AND METHODS. The error bars show deviations between duplicates.