Table 2. Histopathological analyses of inflammatory parameters, demyelination and axonal damage in the spinal cord of C57BL/6 mice at 10, 13, 20 and 50 days after MOG35–55 EAE induction.

	Control EAE	NP-transplanted	P value
Infiltrations/mm2
day 10	0.18±0.2	0.1±0.13	0.5
day 13	1.43±0.5	1.15±0.4	0.32
day 20	7.1±1.4	5.22±0.6	0.044
day 50	5.1±0.9	2.41±0.7	0.006
T-cells/mm2
day 10	2.5±2.9	1.66±2.3	0.65
day 13	19.16±4.2	14.66±4.3	0.047
day 20	152.9±22.7	120.2±11.1	0.016
day 50	108.05±20.9	57.29±13	0.029
Macrophages/mm2
day 10	4.79±6	3.5±4.8	0.73
day 13	40.2±8.5	34.16±5.8	0.24
day 20	240±32.9	190±19.8	0.027
day 50	179.44±15.9	106.04±22.5	0.005
% Axonal injury
day 10	0	0	-
day 13	1.3±0.57	1.23±0.53	0.758
day 20	4.65±1	3.41±0.4	0.038
day 50	5.22±0.83	3.58±0.25	0.024
% Demyelination
day 10	0	0	-
day 13	0.68±0.15	0.6±0.14	0.409
day 20	4.2±0.36	2.82±0.5	0.002
day 50	4.36±0.24	2.85±01.4	0.002