Fig. 2.

Migration of the TLR-ligand DC is poor and can be restored upon addition of PGE₂. Differently matured DC from three to six different donors were added to a fibronectin-coated plate and individual cells were monitored for 60 min for their motility. The migrated distance (in μm) (a) and the activity (the percentage of time the cells were migrating) (b) is plotted for the different maturation cocktails and compared to cDC. Per condition, each symbol represents the mean for each donor (individual donors indicated by different symbols). Means are shown for each maturation cocktail and were compared to cDC (* = p < 0.005)