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. Author manuscript; available in PMC: 2008 Aug 26.
Published in final edited form as: J Am Chem Soc. 2005 Dec 14;127(49):17412–17420. doi: 10.1021/ja055846n

Figure 2.

Figure 2

Synthesis of oxime libraries based on uracil and RCHO. (A) Synthesis of diaminoalkanediol tethers of variable length. (B) Construction of the uracil-oxime library based on the uracil aldehydes (1–3) and a series of aldehyde compounds (RCHO). The products consist of a 1:2:1 mixture of the heterodimer (U^R), and the two homodimers (U^U and R^R) connected via alkane linkers of lengths 2–6. One equivalent of total diaminoalkanediol is added to each reaction. Each linker length is present at one-fifth of the total concentration.