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. Author manuscript; available in PMC: 2008 Aug 26.
Published in final edited form as: J Am Chem Soc. 2005 Dec 14;127(49):17412–17420. doi: 10.1021/ja055846n

Scheme 1.

Scheme 1

Inhibition Mechanisms for 3-(3)-27 and 2-(2)-13 and Uracila

aOnly 3-(3)-27, 2-(2)-13 and uracil have mechanisms that include the kcat′ step. The mechanism for 3-(3)-and uracil do not include the equilibrium constant Kn, and the mechanism for 2-(2)-13 does not include the equilibria Kc or Knc.