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. Author manuscript; available in PMC: 2008 Aug 26.
Published in final edited form as: Biochemistry. 2007 Jan 23;46(3):852–861. doi: 10.1021/bi061923v

Figure 2.

Figure 2

Synthesis of myr-PrP(S230C). Maleimide derivative 1 was prepared by acylation of N-(2-aminoethyl)maleimide with myristoyl chloride in the presence of triethylamine and 4-dimethylaminopyridine (DMAP). The resulting maleimide was attached to PrP(S230C) to yield myr-PrP(S230C).