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Agarose gel electrophoris analysis of the apoptosis-associated internucleosomal DNA fragmentation in Jurkat T cells treated with 54 nM WP762 (its IC75) for 48 h. For comparison, the effect of 180 nM daunorubicin —its IC75— (Table 2), which produced the typical internucleosomal cleavage in apoptotic cells, is shown as a positive control. Qualitatively, the gel suggested the absence of apoptosis in WP762-treated cells.
