Figure 4.

KIF3C accumulation at the proximal region of a ligated sciatic nerve. (A) Ligated and (B) unligated sciatic nerves were stained with anti-KIF3C. After ligation, KIF3C significantly accumulated at the proximal region (left side) of ligation, whereas almost no accumulation was observed at the distal region (right side). The ligated site is indicated by arrows. Ligated sciatic nerve double-stained with anti-KIF3C (C) and a monoclonal antibody against synaptobrevin (D). Only the proximal region with the ligated site on the right is shown in (C) and (D). Scale bar: 50 μm in (A) and (B); 20 μm in (C) and (D).