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Effects of peptide competitors and mutation on the neuritogenic activity of L1 Ig6. DRG cells were cultured on substrate-coated GST-Ig6 or GST-Ig6(KGE) for 20 h and fixed. Approximately 100 neurites were measured and the mean neurite length was calculated. As a control, DRG cells were cultured on GST-Ig6 in the presence of L1 peptide competitors: 1.0 mg/ml of peptide L1-RGD or peptide L1-RAD. Data represent the mean ± SD of three experiments.
