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. 1985 Oct;56(1):333–336. doi: 10.1128/jvi.56.1.333-336.1985

Cross-reactivity between herpes simplex virus glycoprotein B and a 63,000-dalton varicella-zoster virus envelope glycoprotein.

C M Edson, B A Hosler, R A Respess, D J Waters, D A Thorley-Lawson
PMCID: PMC252547  PMID: 2993665

Abstract

Cross-reactive monoclonal antibodies recognizing both herpes simplex virus (HSV) glycoprotein B and a major 63,000-dalton varicella-zoster virus (VZV) envelope glycoprotein were isolated and found to neutralize VZV infection in vitro. None of the other VZV glycoproteins was recognized by any polyclonal anti-HSV serum tested. These results demonstrate that HSV glycoprotein B and the 63,000-dalton VZV glycoprotein share antigenic epitopes and raise the possibility that these two proteins have a similar function in infection.

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Selected References

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