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. 2008 May 7;6(2):39–72. doi: 10.3390/md20080004

Table 2.

Overview of all reported AZA analogs.

Abbrev. Original analog Substituent Name Ref.
AZA1 Azaspiracid 2
AZA2 8-methyl-azaspiracid 14
AZA3 22-desmethyl-azaspiracid 14
AZA4 AZA3 OH 22-desmethyl-3-hydroxy-azaspiracid 13
AZA5 AZA3 OH 22-desmethyl-23-hydroxy-azaspiracid 13
AZA6 22-desmethyl-8-methyl-azaspiracid 15, 16
AZA7 AZA1 OH 3-hydroxy-azaspiracid 16
AZA8 AZA1 OH 23-hydroxy-azaspiracid 16
AZA9 AZA6 OH 22-desmethyl-3-hydroxy-8-methyl-azaspiracid 16
AZA10 AZA6 OH 22-desmethyl-23-hydroxy-8-methyl-azaspiracid 16
AZA11 AZA2 OH 3-hydroxy-8-methyl-azaspiracid 16
AZA12 AZA2 OH 23-hydroxy-8-methyl-azaspiracid 16, 17
AZA13 AZA3 2 OH 22-desmethyl-3,23-dihydroxy-azaspiracid 17
AZA14 AZA1 2 OH 3,23-dihydroxy-azaspiracid 17
AZA15 AZA6 2 OH 22-desmethyl-3,23-dihydroxy-8-methyl-azaspiracid 17
AZA16 AZA2 2 OH 3,23-dihydroxy-8-methyl-azaspiracid 17
AZA17 AZA3 COOH carboxy-22-desmethyl-azaspiracid 15, 17
AZA18 AZA1 COOH carboxy-azaspiracid 17
AZA19 AZA6 COOH carboxy-22-desmethyl-8-methyl-azaspiracid 17
AZA20 AZA2 COOH carboxy-8-methyl-azaspiracid 17
AZA21 AZA3 COOH + OH carboxy-22-desmethyl-3-hydroxy-azaspiracid 17
AZA22 AZA1 COOH + OH carboxy-3-hydroxy-azaspiracid 17
AZA23 AZA6 COOH + OH carboxy-22-desmethyl-3-hydroxy-8-methyl-azaspiracid 17
AZA24 AZA2 COOH + OH carboxy-3-hydroxy-8-methyl-azaspiracid 17
AZA25 AZA3 -H2O 21-22-dehydro-22-desmethyl-azaspiracid 17
AZA26 AZA1 -H2O 21-22-dehydro-azaspiracid 17
AZA27 AZA6 -H2O 21-22-dehydro-22-desmethyl-8-methyl-azaspiracid 17
AZA28 AZA2 -H2O 21-22-dehydro-8-methyl-azaspiracid 17
AZA29 AZA3 COOCH3 22-desmethyl-azaspiracid-1-methyl-ester 17
AZA30 AZA1 COOCH3 Azaspiracid-1-methyl-ester 17
AZA31 AZA6 COOCH3 22-desmethyl-8-methyl-azaspiracid-1-methyl-ester 17
AZA32 AZA2 COOCH3 8-methyl-azaspiracid-1-methyl-ester 17