Win1 and Wak1 act in concert to control stress resistance. Wild-type (WT) (PR109), sty1::ura4 (Δsty1) (JM 1160), wis1::ura4 (Δwis1) (JM 544), wak1::ura4 (Δwak1) (JM 1436), win1–1 (win1–1) (JM1413), or wak1::ura4 win1–1 (Δwak1 win1–1)(JM 1504) cells were grown on YEPD and then streaked to the same medium at 30°C (top left plate) or to the same medium containing 1.5 M sorbitol at 30°C (top right plate) or to YEPD at 37°C (bottom left plate) and incubated for 2 d.