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A model for the role of Win1 in controlling the fission yeast stress-activated Sty1 MAPK. We propose that Win1 controls the activity of Wis1 MAPKK in parallel with the Wak1 MAPKKK and that the Mcs4 response regulator acts upstream of both Wak1 and Win1. We also tentatively suggest that the Wis1 MAPKK may be controlled by an additional Wak1- and Win1-independent pathway.
