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. 1998 Jul 1;188(1):103–117. doi: 10.1084/jem.188.1.103

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Differential methylation of the IFN-γ and IL-3 genes in CD8⁺ T cell clones and independence of clone size. CpG sites in the two promoters are depicted schematically and numbered as described in Fig. 1. Asterisks above the −53 site in the IFN-γ promoter indicate the only CpG site hitherto characterized in T cells. Methylation of the coding (upper line of symbols) and noncoding (lower line of symbols) strands for the IFN-γ and IL-3 promoters are shown for the control cell line FDCP1 and 16 CD8⁺ T cell clones ranging in size from 35 to >256 cells. Methylation patterns were scored as described in Fig. 3.

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