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. 1998 Jul 1;188(1):157–167. doi: 10.1084/jem.188.1.157

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Inhibition of OVA-induced airway hyperresponsiveness after chemokine blockage. Results are shown as the mean ± SEM for Penh before (gray bars) and after (black bars) methacholine provocation (n = 10, two independent experiments). Mice were exposed to an aerosol of methacholine for 1 min, and airway constriction was evaluated for the next 5 min. PBS- or OVA plus irrelevant Ab–treated mice were used as control for OVA-treated littermates in which MIP-1α, eotaxin, MCP-5, or MCP-1 was blocked from days (d) 8 to 21 (A) or at the time points indicated (B).