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. 2008 Aug 4;205(8):1903–1916. doi: 10.1084/jem.20080397

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© 2008 Cosmi et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 1. — Human Th17 clones express the NKT cell marker CD161. (A) Volcano plot representation (log₂ fold change vs. t test p-value) between Th17 and Th1 (left) or Th2 (right) cell gene expression profiles. (B) CD161 mRNA levels were measured by real-time quantitative RT-PCR in Th1, Th2, and Th17 clones. Bars represent mean values ± SE obtained in 10 clones from each type different from those used for the microarray assay. (C) Representative flow cytometric analysis of CD161 surface expression for each type of clone. The gates were placed on the basis of an isotype-matched control mAb. Percentages of gated cells are shown.