Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Aug 4;205(8):1755–1761. doi: 10.1084/jem.20080588

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2008 Takahashi et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jem.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 2. — IL-17R KO mice are less susceptible to TNF-induced shock. TNF was injected i.v. in WT (n = 7) and IL-17R KO (n = 7) mice, and mortality was monitored. Blood samples were taken 3 h after the injection, and serum samples were tested for IL-6 and NO_x. (A and B) Survival curves after 10 and 7.5 μg TNF, respectively. *, P = 0.00175 and **, P = 0.0075 compared with WT control. (C and D) Serum levels of NO_x (***, P = 0.0002; n = 5) and IL-6 (**, P = 0.0017; n = 6) 3 h after injecting 7.5 μg TNF.