Skip to main content
. Author manuscript; available in PMC: 2008 Aug 26.
Published in final edited form as: Chem Rev. 2007 May 27;107(6):2503–2545. doi: 10.1021/cr0509556

Table 43.

Asymmetric hydroformylation reactions of styrene, allyl cyanide, and vinyl acetate with different ligands under solvent-free conditions.

entry ligand conv. (%) b/l ee (%) config.
graphic file with name nihms-63649-t0133.jpg
1 (2R,4R)-Chiraphite 32 10.8 51 R
2 (R,S)-BINAPHOS 35 4.6 81 R
3 (S,S)-Kelliphite 32 9.2 3 S
4 diazaphospholane 73 5.7 80 R
5 (R,R)-Ph-BPE 33 45 92 R
graphic file with name nihms-63649-t0134.jpg
6 (2R,4R)-Chiraphite 74 5.8 13 R
7 (R,S)-BINAPHOS 58 2.1 68 R
8 (S,S)-Kelliphite 99 10.1 66 S
9 diazaphospholane 100 3.9 80 R
10 (R,R)-Ph-BPE 67 7.6 90 R
graphic file with name nihms-63649-t0135.jpg
11 (2R,4R)-Chiraphite 34 204 50 R
12 (R,S)-BINAPHOS 23 7.1 58 S
13 (S,S)-Kelliphite 32 100 75 R
14 diazaphospholane 92 47 95 S
15 (R,R)-Ph-BPE 34 263 82 S