Table 6.
Kinetic resolution of racemic 2,2-disubstituted epoxides under solvent-free conditions.
![]() | ||||
---|---|---|---|---|
Me3SIN3 (equiv) |
i-PrOH (equiv) |
yield (%) | ee (%) | epoxide product |
0.55 | 0.55 | 46 | 85 | ![]() |
0.70 | 0.70 | 48 | 80 | ![]() |
Kinetic resolution of racemic 2,2-disubstituted epoxides under solvent-free conditions.
![]() | ||||
---|---|---|---|---|
Me3SIN3 (equiv) |
i-PrOH (equiv) |
yield (%) | ee (%) | epoxide product |
0.55 | 0.55 | 46 | 85 | ![]() |
0.70 | 0.70 | 48 | 80 | ![]() |