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. 2008 Sep 2;118(10):3470–3477. doi: 10.1172/JCI35114

Figure 1. HSV-1 infection increases Egr-1 expression.

Figure 1

The viral growth (A) and Egr-1 expression assayed by RT-PCR (B) and Western blot (C) analyses were monitored in SK-N-SH cells infected with strain KOS or with UV-inactivated virus (UV). M, molecular weight marker. (D) The brain stem regions of Egr-1+/+ and Egr-1–/– C57BL/6 mice mock infected or infected with strain 294.1 were harvested at day 6 p.i. and stained with DAPI or antibodies against Egr-1 or viral antigen glycoprotein D (gD). Original magnification, ×200. Data are representative of at least 2 experiments.