FIG. 3.

Muscarinic agonists decrease compound postsynaptic potentials (PSPs). A: schematic of experimental setup, in which rostral hemicord is stimulated to elicit compound PSPs. Ipsilateral stimulation produces mainly excitatory PSPs (EPSPs), whereas contralateral stimulation produces mainly inhibitory PSPs (IPSPs). B: an example of an EPSP before (black) and after (red) the local application of muscarine (1 mM). C: compound IPSPs were also reduced after muscarine application. D: the reduction in the PSP area was time locked to application of muscarine, as shown for the PSP from B.